| Registro completo |
| Provedor de dados: |
BJPS
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| País: |
Brazil
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| Título: |
Protective effect of guabiju (Myrcianthes pungens (O. Berg) D. Legrand) and red guava (Psidium cattleyanum Sabine) against cisplatin-induced hypercholesterolemia in rats
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| Autores: |
Nora,Cleice Dalla
Danelli,Daiane
Souza,Lucéia Fátima
Rios,Alessandro de Oliveira
Jong,Erna Vogt de
Flôres,Simone Hickmann
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| Data: |
2014-09-01
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| Ano: |
2014
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| Palavras-chave: |
Guabiju/protective effect
Red guava/protective effect
Myrcianthes pungens (O. Berg) D
Legrand/protective effect
Psidium cattleyanum Sabine/protective effect
Hypercholesterolemia/experimental study
Cisplatin
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| Resumo: |
The present study was the first to examine the protective effect and antioxidant potential of two fruits native to the south of Brazil, namely guabiju (Myrcianthes pungens (O. Berg) D. Legrand) and red guava (Psidium cattleyanumSabine), with respect to reducing the effects of cisplatin-induced hypercholesterolemia in male Wistarrats. The cisplatin-treated animals showed high glucose, LDL cholesterol, oxidized LDL cholesterol and total cholesterol levels. These native fruits reversed the increase in these parameters. The fat levels in the liver improved with supplementation with the fruits, and there were no differences in the thiobarbituric acid reactive substances (TBARS), creatinine, urea or HDL cholesterol levels, nor in the weight of the organs analyzed, indicating that the dose used did not affect these markers.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300483
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| Editor: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
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| Relação: |
10.1590/S1984-82502014000300006
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Pharmaceutical Sciences v.50 n.3 2014
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| Direitos: |
info:eu-repo/semantics/openAccess
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